Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Isocyanate → 1-(Methylcarbamoyl)-3-[(4-chlorophenyl)thio]-azacycloheptan-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Isocyanate | HCID 12228 | — |
| 반응물 | Di-n-butyldilauryltin | HCID 9809426 | — |
| 반응물 | HCID 13268904 | HCID 13268904 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-(Methylcarbamoyl)-3-[(4-chlorophenyl)thio]-azacycloheptan-2-one | HCID 20448003 | — |
반응 단계
25.6 g (0.1 mol) of 3-[(4-chlorophenyl)thio]-azacycloheptan-2-one together with 5.7 g (0.1 mol) of methyl isocyanate and 100 mg of dibutyl-tin dilaurate in 150 ml of absolute toluene are boiled under reflux for 5 hours. After the mixture has cooled, the solvent is stripped off in vacuo, and the oily residue is used for further reactions.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04468392 |
| 출처 데이터셋 | uspto-grants-1984_08 |
| ORD ID | ord-7067370980904d529ab71b7ad55b6b99 |
| 출처 메모 | uspto-grants-1984_08 |