Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Amino-5-methylisoxazole → 5,6-Dihydro-4-hydroxy-2,6-dimethyl-N-(5-methyl-3-isoxazolyl)-1,1-dioxo-2H-1,2,6-thiadiazine-3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Amino-5-methylisoxazole | HCID 66172 | — |
| 반응물 | methyl 5,6-dihydro-4-hydroxy-2,6-dimethyl-1,1-dioxo-2H-1,2,6-thiadiazine-3-carboxylate | HCID 54719676 | — |
| 생성물 | 5,6-Dihydro-4-hydroxy-2,6-dimethyl-N-(5-methyl-3-isoxazolyl)-1,1-dioxo-2H-1,2,6-thiadiazine-3-carboxamide | HCID 54719677 | 49% |
반응 단계
The synthesis was effected analogously to Example 1 using in each case 1.0 equivalent of methyl 5,6-dihydro-4-hydroxy-2,6-dimethyl-1,1-dioxo-2H-1,2,6-thiadiazine-3-carboxylate and 3-amino-5-methylisoxazole. Recrystallisation from a diisopropyl ether/tetrahydrofuran mixture gives the title compound in a yield of 49%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05411955 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-08f064fa14be4ae4821b076e7a759930 |
| 출처 메모 | uspto-grants-1995_05 |