2-Methyl-2-propenyl 5-bromo-3-(2-methyl-2-propenyl)-2-hydroxybenzoate → 5-Bromo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acid

HRID 358830노트

반응식

HRID 358830 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH2:16][C:17]([CH3:19])=[CH2:18])[C:5]([OH:15])=[C:6]([CH:14]=1)[C:7]([O:9]CC(C)=C)=[O:8]>C(O)=O>[Br:1][C:2]1[CH:14]=[C:6]([C:7]([OH:9])=[O:8])[C:5]2[O:15][C:17]([CH3:19])([CH3:18])[CH2:16][C:4]=2[CH:3]=1

참가 물질

3

반응물 1

HCID 157287372-Methyl-2-propenyl 5-bromo-3-(2-methyl-2-propenyl)-2-hydroxybenzoate

생성물 1

HCID 148384015-Bromo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acid수율 20%

시약·촉매·용매 1

HCID 284Formic Acid용매

실험 절차

The title intermediate was prepared in 20% yield from 2-methyl-2-propenyl 5-bromo-3-(2-methyl-2-propenyl) -2-hydroxybenzoate upon heating at reflux with 90% formic acid.

후처리

  1. temperatureupon heating

출처 및 근거

ORD 기록
ord-f34d7c884f024072aaf5bf0801dcd51f
출처 데이터셋
uspto-grants-1991_03
특허 번호
US04997956

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