3-Methyl-2-buten-1-OL → Ethyl 3,3-dimethylpent-4-enoate

HRID 359164

반응식

HRID 359164 반응식
[CH3:1][C:2]([CH3:6])=[CH:3][CH2:4]O.[C:7]([O-:13])([O-])([O:9][CH2:10][CH3:11])[CH3:8]>C1(C=CC(O)=CC=1)O>[CH3:1][C:2]([CH3:6])([CH:3]=[CH2:4])[CH2:8][C:7]([O:9][CH2:10][CH3:11])=[O:13]

참가 물질

4

반응물 2

HCID 111733-Methyl-2-buten-1-OLHCID 86598186Ethyl ortho-acetate2회

생성물 1

HCID 82262Ethyl 3,3-dimethylpent-4-enoate수율 75.1%

시약·촉매·용매 1

HCID 785Hydroquinone촉매

실험 절차

A mixture of 12.9 g (0.15 mole) of 3-methyl-2-buten-1-ol, 48.6 g (0.3 mole) of ethyl orthoacetate and 0.5 g of hydroquinone was heated at 140° for 20 hours with stirring. Ethanol was removed by distillation during the heating. At the end of 20 hours, the mixture was distilled under reduced pressure to give, after removal of unreacted ethyl orthoacetate, 17.6 g (75% yield) of ethyl 3,3-dimethyl-4-pentenoate, b.p. 74°-78°/55 mm.

후처리

  1. temperaturewas heated at 140° for 20 hours
  2. customEthanol was removed by distillation during the heating
  3. distillationAt the end of 20 hours, the mixture was distilled under reduced pressure
  4. customto give

출처 및 근거

ORD 기록
ord-975f344e2ddf41008236f96ee7ec480b
출처 데이터셋
uspto-grants-1991_03
특허 번호
US04999451

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