3-Methyl-2-buten-1-OL → Ethyl 3,3-dimethylpent-4-enoate
반응식
[CH3:1][C:2]([CH3:6])=[CH:3][CH2:4]O.[C:7]([O-:13])([O-])([O:9][CH2:10][CH3:11])[CH3:8]>B(O)(O)O.C(O)C>[CH3:1][C:2]([CH3:6])([CH:3]=[CH2:4])[CH2:8][C:7]([O:9][CH2:10][CH3:11])=[O:13]참가 물질
5
실험 절차
A mixture of 4.3 g of 3-methyl-2-buten-1-ol, 16.2 g of ethyl orthoacetate and 86 mg of boric acid was heated for 2 hours at 120° with stirring, during which ethanol was evolved and removed. The temperature was then increased to 145°-150° where it was maintained for an additional 8 hours. When ethanol evolution ceased, the mixture was distilled to separate unreacted ethyl orthoacetate from 6.25 g (80% yield) of ethyl 3,3-dimethyl-4-pentenoate, b.p. 78°-80°/51 mm.
후처리
- temperaturewas heated for 2 hours at 120°
- customremoved
- temperatureThe temperature was then increased to 145°-150° where it
- temperaturewas maintained for an additional 8 hours
- distillationthe mixture was distilled
출처 및 근거
- ORD 기록
- ord-f83c2bee929a48e5808c646049e1d2ed
- 출처 데이터셋
- uspto-grants-1991_03
- 특허 번호
- US04999451
반응 노트
불러오는 중…