Acetone Cyanohydrin → 2-((4-Hydroxybutyl)amino)-2-methylpropanenitrile

HRID 35945

반응식

HRID 35945 반응식
[CH3:1][C:2]([CH3:6])(O)[C:3]#[N:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12]>C(Cl)Cl>[OH:12][CH2:11][CH2:10][CH2:9][CH2:8][NH:7][C:2]([CH3:6])([CH3:1])[C:3]#[N:4]

참가 물질

4

반응물 2

HCID 6406Acetone CyanohydrinHCID 258684-Amino-1-butanol

생성물 1

HCID 155119612-((4-Hydroxybutyl)amino)-2-methylpropanenitrile

시약·촉매·용매 1

HCID 6344Dichloromethane용매

반응 조건

온도
20 °C

실험 절차

220 μl of acetone cyanohydrin and 200 μl of 4-amino 1-butanol were mixed together with stirring for 16 hours at 20° C. and then was diluted with 2 ml of methylene chloride, dried, filtered and the filtrate was concentrated under reduced pressure to obtain the propanonitrile which was used as is for the following stage.

후처리

  1. customdried
  2. filtrationfiltered
  3. concentrationthe filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-af507ea0ea16417b8b65e6f6abd9ae52
출처 데이터셋
uspto-grants-1995_05
특허 번호
US05411981

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