참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2,3,4,5,6-Pentafluorobenzylidene rhodanine | HCID 4907291 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4,5,6,7-Tetrafluorobenzothiophen-2-carboxylic acid | HCID 10988683 | — |
반응 단계
78 g of 2,3,4,5,6-pentafluorobenzylidene rhodanine were added in small portions to a stirred solution of 68 g of NaOH in 300 ml of water. The resultant clear red solution was heated to 90° C. for one hour, cooled in ice, acidified with concentrated HCl, and the cream coloured solid which was produced was filtered and washed. The crude product (59 g) was purified by sublimation to give 4,5,6,7-tetrafluorobenzothiophen-2-carboxylic acid having a melting point of 200° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05001163 |
|---|
| 출처 데이터셋 | uspto-grants-1991_03 |
|---|
| ORD ID | ord-6cf3f054d9ff4d0bb059e798eeecbbd0 |
|---|
| 출처 메모 | uspto-grants-1991_03 |
|---|
