Indole-3-pyruvic acid → HCID 12457675, 화합물
반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][C:11](=[O:15])[C:12]([OH:14])=[O:13])=[CH:2]1.[CH2:16]1CCN2C(=NCCC2)C[CH2:17]1.C(Br)C>C1C=CC=CC=1>[CH2:16]([O:13][C:12](=[O:14])[C:11]([CH2:10][C:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[NH:1][CH:2]=1)=[O:15])[CH3:17]참가 물질
5
실험 절차
Following the same method as previously described, 1,0 g 3-indole-pyruvic acid were reacted with 1,5 ml DBU and 790 microliters ethylbromide. In this case the benzene solution appeared red orange. After flash chromatography purification the ethyl ester was obtained with a yield of about 70%.
후처리
- customAfter flash chromatography purification the ethyl ester
- customwas obtained with a yield of about 70%
출처 및 근거
- ORD 기록
- ord-b950a389228e4d7da502945220a05509
- 출처 데이터셋
- uspto-grants-1991_03
- 특허 번호
- US05002963
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