Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Indole-3-pyruvic acid → HCID 54134943, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Indole-3-pyruvic acid | HCID 803 | — |
| 반응물 | Cyclohexylamine | HCID 7965 | — |
| 반응물 | 4-Methylmorpholine | HCID 7972 | — |
| 반응물 | 1-Hydroxybenzotriazole | HCID 75771 | — |
| 반응물 | Dimethylazanide | HCID 182180 | — |
| 용매 | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| 생성물 | HCID 54134943 | HCID 54134943 | — |
반응 단계
The same method as described in Example 7 was followed for the preparation of N,N-dimethylamide. 500 mg 3-indolepyruvic acid were reacted with 400 ml HOBt and 570 ml EDC.HCl. 340 microliters of freshly distilled cyclohexylamine and 325 microliters NMM were added to the solution, which was reacted for 5 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05002963 |
| 출처 데이터셋 | uspto-grants-1991_03 |
| ORD ID | ord-ab4f0216453f46f89472cb195305881f |
| 출처 메모 | uspto-grants-1991_03 |