Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanolamine → N-(2-hydroxyethyl)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | Ethyl Nicotinate | HCID 69188 | — |
| 생성물 | N-(2-hydroxyethyl)nicotinamide | HCID 72663 | 85.1% |
반응 단계
A solution of 49.2 g (0.32525 mol) ethyl nicotinate and 72 g (1.17 mol) ethanolamine was heated at 70° C. for 60 hours. The excess ethanolamine was removed under reduced pressure and the resulting viscous cream oil was stirred with ether for 48 hours. The resulting white solid was removed by filtration, affording 46 g (85.1%) of the title compound melting at 75°-78° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05002935 |
| 출처 데이터셋 | uspto-grants-1991_03 |
| ORD ID | ord-d75f9f418ccc4c9a9128f3b7711a460b |
| 출처 메모 | uspto-grants-1991_03 |