Chlorine → 1,3-Isobenzofurandione, 5-fluoro-

반응식

[F:1][C:2]1(F)[CH2:12][CH2:11][CH:5]2[C:6]([O:8][C:9](=[O:10])[CH:4]2[CH2:3]1)=[O:7].ClCl>>[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[O:10])[O:8][C:6](=[O:7])[C:5]2=[CH:11][CH:12]=1

참가 물질

반응물 2

HCID 24526Chlorine

HCID 140082491,3-Isobenzofurandione, 5,5-difluorohexahydro-

생성물 1

HCID 675721,3-Isobenzofurandione, 5-fluoro-수율 80%

실험 절차

The procedure of Example III was repeated except that the feed was 4,4-difluorohexahydrophthalic anhydride, the vapor temperature was 240° C., reaction temperature was 255° C., the organic rate was 0.5 grams/minute, and the chlorine rate was 183 ml/min. The product, 4-fluorophthalic anhydride, was produced in 80% yield and 90% purity.

후처리

customwas 240° C.
customreaction temperature
customwas 255° C.

출처 및 근거

ORD 기록: ord-032b60dd621946d4a93f66b106cb3332
출처 데이터셋: uspto-grants-1991_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05003088

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