Anisole → HCID 178503585, 화합물

HRID 359928노트

반응식

HRID 359928 반응식
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](=[CH:11][CH:12]=1)[N:7]=[C:8](C)[N:9]=2.[C:13]1(OC)C=CC=CC=1.[F:21][C:22]([F:29])([F:28])[S:23]([O:26]C)(=[O:25])=[O:24]>C(OCC)(=O)C>[F:21][C:22]([F:29])([F:28])[S:23]([O-:26])(=[O:25])=[O:24].[CH3:13][N:7]1[C:6]2=[CH:11][CH:12]=[C:2]([CH3:1])[CH:3]=[CH:4][C:5]2=[NH+:9][CH:8]1[S:23][CH3:22]

참가 물질

5

반응물 3

HCID 7519AnisoleHCID 9526Methyl triflateHCID 20064366HCID 20064366, 화합물

생성물 1

HCID 178503585HCID 178503585, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

27 g of 6-methyl-2-methylcycloheptimidazole was added to 100 ml of anisole and stirred under cooling with ice. Next, 28 g of methyl trifluoromethanesulfonate was dropwise added and further everything was stirred under cooling with ice. After everything was stirred for 1 hour at room temperature, 200 ml of ethyl acetate was added, and the crystals precipitated were separated by filtration and dried.

후처리

  1. temperatureunder cooling with ice
  2. stirringfurther everything was stirred
  3. temperatureunder cooling with ice
  4. stirringAfter everything was stirred for 1 hour at room temperature
  5. customthe crystals precipitated
  6. customwere separated by filtration
  7. customdried

출처 및 근거

ORD 기록
ord-372a23129d09481db7728c198ba66752
출처 데이터셋
uspto-grants-1991_03
특허 번호
US05003077

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