Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroform → 2,5-Dimethoxymethyl-5-methyl-1,3-dioxane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 2-(Methoxymethyl)-2-methylpropane-1,3-diol | HCID 88886 | — |
| 반응물 | Methoxyacetaldehyde | HCID 91563 | — |
| 반응물 | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2,5-Dimethoxymethyl-5-methyl-1,3-dioxane | HCID 14597944 | 91% |
반응 단계
A mixture of 670 g (5 moles) of 2-methoxymethyl2-methyl-1,3-propanediol, 479 g (5.5 moles) of 85% strength methoxyacetaldehyde and 250 ml of chloroform was heated with 10 g of pyridinium p-toluenesulfonate under a water separator until water no longer separated off. The solution was deionized using a mixed-bed ion exchanger, the solvent was stripped off under reduced pressure and the residue was subjected to fractional distillation under reduced pressure. 864 g (91% yield) of 2,5-dimethoxymethyl-5-methyl-1,3-dioxane of boiling point 95° C./10 mbar were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05003089 |
| 출처 데이터셋 | uspto-grants-1991_03 |
| ORD ID | ord-88ff168f230848ee9c90174d2615cc11 |
| 출처 메모 | uspto-grants-1991_03 |