참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Tridecane | HCID 12388 | — |
| 반응물 | 4,5-Difluorophthalic Anhydride | HCID 639745 | — |
| 용매 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 생성물 | 3,4-Difluorobenzoic acid | HCID 99166 | 85% |
반응 단계
4,5-difluorophthalic anhydride (0.5 grams, 2.7 mmole) was added to a slurry of cupric oxide (5% by weight of starting material) in 5 ml. of N-methyl-2-pyrrolidone. n-tridecane (0.25 grams) was added as an internal standard. The mixture was heated to 190° C. for 3 hours, at which time GC analysis indicated complete consumption of the starting material and conversion to 3,4-difluorobenzoic acid in an 85% yield, based upon the internal standard, corrected for response factors.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05003103 |
|---|
| 출처 데이터셋 | uspto-grants-1991_03 |
|---|
| ORD ID | ord-622f7889c5fd4a34bcfd850228f6c47e |
|---|
| 출처 메모 | uspto-grants-1991_03 |
|---|
