Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl chloroformate → 4''-[2-Butyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-biphenyl-2-sulfonic acid benzyloxycarbonylamide(L-162620)
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl chloroformate | HCID 10387 | — |
| 반응물 | Butyl chloroformate | HCID 61140 | — |
| 반응물 | 7-methyl-2-propyl-3-[2'-(aminosulfonyl)[1,1']-biphenyl-4-yl]methyl-6-[(1-oxobutyl)amino]-3H-imidazo[4,5-b]pyridine | HCID 19939752 | — |
| 생성물 | 4''-[2-Butyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-biphenyl-2-sulfonic acid benzyloxycarbonylamide(L-162620) | HCID 9917399 | — |
반응 단계
The title compound was prepared from 7-methyl-2-propyl-3-[2'-(aminosulfonyl)[1,1']-biphenyl-4-yl]methyl-6-[(1-oxobutyl)amino]-3H-imidazo[4,5-b]pyridine as described in Example 30 substituting the reagent benzyl chloroformate for butyl chloroformate in Step 5. FAB MS for C35H37N5SO5 : M+ +1=640.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05412097 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-f126533a13fb404a9768c31baa65791a |
| 출처 메모 | uspto-grants-1995_05 |