HCID 86753651, 화합물 → methyl 4,7-dimethoxy-1H-indole-2-carboxylate

HRID 361610노트

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HRID 361610 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH3:10])=[CH:5][C:4]=1[C:11](C1C=CC=CC=1)=[C:12]([N:17]=[N+]=[N-])[C:13]([O:15][CH3:16])=[O:14]>C1(C)C(C)=CC=CC=1>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH3:10])=[C:5]2[C:4]=1[CH:11]=[C:12]([C:13]([O:15][CH3:16])=[O:14])[NH:17]2

참가 물질

3

반응물 1

HCID 86753651HCID 86753651, 화합물

생성물 1

HCID 4714975methyl 4,7-dimethoxy-1H-indole-2-carboxylate수율 74.7%

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

A solution of 1.5 g (6.84 mmol) of the above-obtained methyl 2,5-dimethoxyphenyl-α-azidocinnamate in 300 ml of xylene was refluxed for 4 hours. After distilling off xylene, the residue was recrystallized from methanol to provide 1.01 g of the title compound (74.7%).

후처리

  1. distillationAfter distilling off xylene
  2. customthe residue was recrystallized from methanol

출처 및 근거

ORD 기록
ord-031bcfff8d504574be5d9be92800f607
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05866594

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