Water → Propionitrile, 3-(p-chlorophenoxy)-

HRID 361716노트

반응식

HRID 361716 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[C:9](#[N:12])[CH:10]=[CH2:11].[OH-].C([N+](C)(C)C)C1C=CC=CC=1.O>CO>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:11][CH2:10][C:9]#[N:12])=[CH:4][CH:3]=1

참가 물질

6

반응물 4

HCID 962WaterHCID 46844-ChlorophenolHCID 7855AcrylonitrileHCID 66854Benzyltrimethylammonium hydroxide

생성물 1

HCID 96550Propionitrile, 3-(p-chlorophenoxy)-

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of p-chlorophenol (25 g), acrylonitrile (30 ml) and a solution of benzyltrimethylammonium hydroxide (8 ml of a 40 wt % solution in methanol) were heated at reflux over the weekend. The reaction mixture was poured into water and extracted with ethyl acetate. The ethyl acetate extract was dried and evaporated to give 3-(4-chlorophenoxy)propionitrile.

후처리

  1. temperatureat reflux over the weekend
  2. extractionextracted with ethyl acetate
  3. extractionThe ethyl acetate extract
  4. customwas dried
  5. customevaporated

출처 및 근거

ORD 기록
ord-525446a4cf4c4e54862c339880ef50f7
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05866611

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