Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lithium azide → [2'-(N-t-Butylsulfamoyl)biphenyl-4-yl]methyl azide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lithium azide | HCID 88163 | — |
| 반응물 | [2'-(N-t-Butylsulfamoyl)biphenyl-4-yl]methyl bromide | HCID 15282100 | — |
| 생성물 | [2'-(N-t-Butylsulfamoyl)biphenyl-4-yl]methyl azide | HCID 10427616 | 74% |
반응 단계
Reaction of [2'-(N-t-butylsulfamoyl)biphenyl-4-yl]methyl bromide (from Step D) with lithium azide was carried out according to the procedure of Example 9, Step A. The crude product was purified by flash chromatography on silica gel (elution with 10% EtOAc in hexane) to give a 74% yield of the title compound as a white solid; satisfactory purity (by TLC in 9:1 hexane-EtOAc) for use in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05411980 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-5b582a3dfc904b129bd9856a7382c53f |
| 출처 메모 | uspto-grants-1995_05 |