Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Nitrophenyl)hydrazine → 5-Cyclopropyl-2,4-dihydro-2-(2-nitrophenyl)-3H-1,2,4-triazol-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Nitrophenyl)hydrazine | HCID 3314739 | — |
| 반응물 | HCID 54370041 | HCID 54370041 | — |
| 용매 | Dichloromethane methanol | HCID 21226129 | — |
| 생성물 | 5-Cyclopropyl-2,4-dihydro-2-(2-nitrophenyl)-3H-1,2,4-triazol-3-one | HCID 135720084 | 69% |
반응 단계
By the procedure of Example 4, Step C, 2-nitrophenylhydrazine was reacted with ethyl N-(carbethoxy)cyclopropanecarboximidate. After work-up, the residue was purified by flash chromatography on silica gel (150 mL for 2.0 mmole, eluted with 1.5% MeOH/CH2Cl2) to give the desired material as a yellow foam in 69% yield, homogeneous by TLC in 5% MeOH/CH2Cl2, mass spectrum (FAB) m/e 247 (M+1)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05411980 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-bba17d0917914d9fb6f8e3e9787e2847 |
| 출처 메모 | uspto-grants-1995_05 |