Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl chloroformate → Benzoic acid, 4-(1-methylethenyl)-, methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl chloroformate | HCID 6586 | — |
| 반응물 | 4-Chloro-alpha-methylstyrene | HCID 74381 | — |
| 반응물 | Magnesium | HCID 5462224 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Benzoic acid, 4-(1-methylethenyl)-, methyl ester | HCID 11275336 | — |
반응 단계
Preparation of the Grignard compound of 4-chloro-α-methylstyrene by means of Rieke magnesium in THF under reflux and subsequent reaction with 0.95 equivalents of methyl chloroformate at RT. Aqueous working up, extraction with ethyl acetate and column chromatography using cyclohexane/ethyl acetate 85:15 affords methyl 4-isopropenylbenzoate as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05869531 |
| 출처 데이터셋 | uspto-grants-1999_02 |
| ORD ID | ord-b9804facfb484b00bae18c748b7636e4 |
| 출처 메모 | uspto-grants-1999_02 |