Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 3-(4-Fluorophenyl)propionyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-(4-Fluorophenyl)propionic acid | HCID 136302 | — |
| 생성물 | 3-(4-Fluorophenyl)propionyl chloride | HCID 21964258 | 96.3% |
반응 단계
A mixture of 3-(4-fluorophenyl)propionic acid (275.1 g, 1.6 mol) and thionyl chloride (300 mL, 4.1 mol) was heated to reflux for 3 h, cooled to room temperature and distilled under aspirator vacuum to give 287.6 g (96%) of 3-(4-fluorophenyl)propionyl chloride as a pale pink oil, b.p., 120°-122° C./15 mm Hg:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05872118 |
| 출처 데이터셋 | uspto-grants-1999_02 |
| ORD ID | ord-b35a9893a28d48c2b269c358caf2e0f2 |
| 출처 메모 | uspto-grants-1999_02 |