Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 3-(2-fluorophenyl)prop-2-enoate → Ethyl 3-(2-fluorophenyl)propanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 3-(2-fluorophenyl)prop-2-enoate | HCID 590919 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Platinum oxide monohydrate | HCID 86587499 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Ethyl 3-(2-fluorophenyl)propanoate | HCID 14879014 | 99% |
반응 단계
A mixture of ethyl 2-fluorocinnamate (29.25 g, 0.176 mol) and platinum oxide hydrate (0.25, EM Scientific) in 95% ethanol (150 mL) was placed on a Parr hydrogenation apparatus and shaken under 2-4 atm at hydrogen pressure. After the appropriate amount of hydrogen was consumed, the catalyst was removed by filtration, and the filtrate was concentrated in vacuo to give 29.39 g (99%) of crude ethyl 3-(2-fluorophenyl)propionate. This material was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05872118 |
| 출처 데이터셋 | uspto-grants-1999_02 |
| ORD ID | ord-804027412b4e4b3593bfa9c776543599 |
| 출처 메모 | uspto-grants-1999_02 |