Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glycine → Glycine, N-dodecyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glycine | HCID 750 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1-Bromododecane | HCID 8919 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | Glycine, N-dodecyl- | HCID 16771 | 26.3% |
반응 단계
Glycine was dissolved in a 2:1 mixture by volume of IPA and water. Triethylamine and 1-bromododecane were added to the solution successively and the mixture was kept stirring for more than 7 days. After the solvent was removed, THF was added to the remaining material. Triethylamine hydrobromide was removed by filtration and the filtrate was concentrated. N-n-dodecylglycine was obtained from the concentrated solution by separation and purification by column chromatography with the yield of 26.3%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05413794 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-2d8987052d2b49178f764ccb79a5ad51 |
| 출처 메모 | uspto-grants-1995_05 |