Sodium Carbonate → 5-Phenyl-2-picoline N-oxide
반응식
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1C=C(Cl)C=C(C(OO)=[O:22])C=1.C([O-])([O-])=O.[Na+].[Na+]>C(Cl)Cl>[C:1]1([C:7]2[CH:8]=[N+:9]([O-:22])[C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1참가 물질
5
실험 절차
A solution of 3-phenyl-6-methyl pyridine (2.36 g, 13.95 mmol), in CH2Cl2 (40 mL) at 0° C. was treated with MCPBA (3.58 g, 13.95 mmol) for 1 hour. Saturated aq. Na2CO3 (50 mL) was added and the reaction was extracted with CH2Cl2 (20 mL). The organic extracts were dried (MgSO4), and the solvent evaporated in vacuo to afford the title compound.
후처리
- extractionthe reaction was extracted with CH2Cl2 (20 mL)
- dry with materialThe organic extracts were dried (MgSO4)
- customthe solvent evaporated in vacuo
출처 및 근거
- ORD 기록
- ord-05a8840426d74b2e8630c01407e52f00
- 출처 데이터셋
- uspto-grants-1999_02
- 특허 번호
- US05872136
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