Sodium Carbonate → 5-Phenyl-2-picoline N-oxide

HRID 363196노트

반응식

HRID 363196 반응식
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1C=C(Cl)C=C(C(OO)=[O:22])C=1.C([O-])([O-])=O.[Na+].[Na+]>C(Cl)Cl>[C:1]1([C:7]2[CH:8]=[N+:9]([O-:22])[C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

5

반응물 3

HCID 10340Sodium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 767442-Methyl-5-phenylpyridine

생성물 1

HCID 149805285-Phenyl-2-picoline N-oxide

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of 3-phenyl-6-methyl pyridine (2.36 g, 13.95 mmol), in CH2Cl2 (40 mL) at 0° C. was treated with MCPBA (3.58 g, 13.95 mmol) for 1 hour. Saturated aq. Na2CO3 (50 mL) was added and the reaction was extracted with CH2Cl2 (20 mL). The organic extracts were dried (MgSO4), and the solvent evaporated in vacuo to afford the title compound.

후처리

  1. extractionthe reaction was extracted with CH2Cl2 (20 mL)
  2. dry with materialThe organic extracts were dried (MgSO4)
  3. customthe solvent evaporated in vacuo

출처 및 근거

ORD 기록
ord-05a8840426d74b2e8630c01407e52f00
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05872136

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