Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 1,3-Di-cyclopropylmethyl-8-chloroxanthine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Chlorine monoxide | HCID 24646 | — |
| 반응물 | 1,3-Dicyclopropylmethyl-8-nitro xanthine | HCID 9857658 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1,3-Di-cyclopropylmethyl-8-chloroxanthine | HCID 9814657 | — |
반응 단계
1,3-Di-cyclopropylmethyl-8-nitro xanthine (6 g, 0,023 mol) was dissolved in dimethylformamide (20 ml) and reacted with phosporous oxychloride (14 g) for 1 hour at 120° C. The mixture was then treated with water and stirred for 1 hour at room temperature. The precipitate was filtered off, dissolved in ethyl acetate, dried over anhydrous sodium sulphate and the solvent was removed in vacuo, yield 2.5 g (40%), m.pt. 220° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05734051 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-5a647d1ec9cd418397bbe1ea009898ce |
| 출처 메모 | uspto-grants-1998_03 |