(Aminomethyl)phosphonic acid → Glyphosate

HRID 363808

반응식

HRID 363808 반응식
[NH2:1][CH2:2][P:3](=[O:6])([OH:5])[OH:4].O.[C:8]([OH:12])(=[O:11])[CH:9]=O>[Pd]>[NH2:1][CH2:2][P:3](=[O:4])([OH:6])[OH:5].[CH2:9]([NH:1][CH2:2][P:3]([OH:5])([OH:4])=[O:6])[C:8]([OH:12])=[O:11]

참가 물질

5

반응물 2

HCID 14017(Aminomethyl)phosphonic acidHCID 15620607Glyoxylic acid, monohydrate

생성물 2

HCID 3496GlyphosateHCID 14017(Aminomethyl)phosphonic acid

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

Aminomethylphosphonic acid was reductively alkylated with glyoxylic acid hydrate under catalytic hydrogenation conditions in the manner described in Example 2, except that the catalyst used was palladium metal (0.05 g), and the pH of the initial reaction mixture was 4.5. A 27% conversion of aminomethylphosphonic acid was obtained with a 93.7% selectivity to glyphosate.

후처리

  1. customthe pH of the initial reaction mixture

출처 및 근거

ORD 기록
ord-6b0ffd800a764d7a9a88d4527dff1c5a
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05874612

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