(Aminomethyl)phosphonic acid → Glyphosate
반응식
[NH2:1][CH2:2][P:3](=[O:6])([OH:5])[OH:4].O.[C:8]([OH:12])(=[O:11])[CH:9]=O>[Pd]>[NH2:1][CH2:2][P:3](=[O:4])([OH:6])[OH:5].[CH2:9]([NH:1][CH2:2][P:3]([OH:5])([OH:4])=[O:6])[C:8]([OH:12])=[O:11]참가 물질
5
실험 절차
Aminomethylphosphonic acid was reductively alkylated with glyoxylic acid hydrate under catalytic hydrogenation conditions in the manner described in Example 2, except that the catalyst used was palladium metal (0.05 g), and the pH of the initial reaction mixture was 4.5. A 27% conversion of aminomethylphosphonic acid was obtained with a 93.7% selectivity to glyphosate.
후처리
- customthe pH of the initial reaction mixture
출처 및 근거
- ORD 기록
- ord-6b0ffd800a764d7a9a88d4527dff1c5a
- 출처 데이터셋
- uspto-grants-1999_02
- 특허 번호
- US05874612
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