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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 364048생성일: 2026년 10월 25일

2-(((1-Benzylpyrrolidin-3-yl)methyl)amino)ethanol → 2-[(3-Pyrrolidinylmethyl)amino]ethanol

https://huagongshe.com/reaction/364048

반응식

참여 물질

역할이름HCID투입량
반응물2-(((1-Benzylpyrrolidin-3-yl)methyl)amino)ethanolHCID 14280888—
반응물HCID 178418361HCID 178418361—
촉매PalladiumHCID 23938—
용매MethanolHCID 887—
생성물2-[(3-Pyrrolidinylmethyl)amino]ethanolHCID 1349180357.5%

반응 단계

A mixture of 32.32 g of 2-[[[1-(phenylmethyl)3-pyrrolidinyl]methyl]amino]ethanol, 330 ml of methanol and 3 g of 20% palladium on charcoal was shaken in an atmosphere of hydrogen at about 50 psi and at room temperature for 18 hours. The solvents were then removed at reduced pressure. The residue was distilled under vacuum (bp 129°-131° C. 1.5 mm Hg) to give 11.43 g of 2-[(3-pyrrolidinyl methyl)amino] ethanol.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04604401
출처 데이터셋uspto-grants-1986_08
ORD IDord-999c7c4945a147c4b5b1ed4dd7eaeba5
출처 메모uspto-grants-1986_08