Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3,4-Dimethoxyphenyl)acetic acid → (3,4-Dimethoxyphenyl)acetyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3,4-Dimethoxyphenyl)acetic acid | HCID 7139 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | (3,4-Dimethoxyphenyl)acetyl chloride | HCID 3604458 | — |
반응 단계
Thionyl chloride (600 ml) is added dropwise, with stirring, over a period of 2 hours, to a suspension of 3,4-dimethoxy-phenylacetic acid (549.4 g) in methylene chloride (600 ml). After the development of gas has ended (16 hours) the mixture is refluxed for a further hour. After the highly volatile components have been removed the residue is distilled in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04604389 |
| 출처 데이터셋 | uspto-grants-1986_08 |
| ORD ID | ord-84c79170daf541418aa1ecc3cbc7f128 |
| 출처 메모 | uspto-grants-1986_08 |