Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | n-(2,2-Dimethoxyethyl)-2-(3,4-dimethoxyphenyl)acetamide | HCID 13092500 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | 1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one | HCID 1482373 | — |
반응 단계
A solution of N-(2,2-dimethoxyethyl)-3,4-dimethoxy-phenylacetamide (600.6 g) in concentrated hydrochloric acid (3 liters) is mixed with glacial acetic acid (3 liters). After being left to stand for 17 hours at ambient temperature and mixture is poured onto ice. The crystals obtained are suction filtered, washed with water until neutral and dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04604389 |
| 출처 데이터셋 | uspto-grants-1986_08 |
| ORD ID | ord-6c570c39b0344cbfbe69dbff20377c7a |
| 출처 메모 | uspto-grants-1986_08 |