N-Benzylisatoic anhydride → 3-(o-benzylaminobenzoyl)-3,4-dihydrophthalazin-1(2H)-one

반응식

[C:1]1(=[O:11])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][NH:3][NH:2]1.[CH2:12]([N:19]1C(=O)O[C:22](=[O:23])[C:21]2=[CH:27][CH:28]=[CH:29][CH:30]=[C:20]12)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH2:12]([NH:19][C:20]1[CH:30]=[CH:29][CH:28]=[CH:27][C:21]=1[C:22]([N:3]1[CH2:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:1](=[O:11])[NH:2]1)=[O:23])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

참가 물질

반응물 2

HCID 520756N-Benzylisatoic anhydride

HCID 122144653,4-Dihydrophthalazin-1(2H)-one

생성물 1

HCID 136703973-(o-benzylaminobenzoyl)-3,4-dihydrophthalazin-1(2H)-one

실험 절차

3,4-Dihydrophthalazin-1(2H)-one was reacted with N-benzylisatoic anhydride according to the general procedure above to produce 3-(o-benzylaminobenzoyl)-3,4-dihydrophthalazin-1(2H)-one as a colorless solid, mp 206°-208° C.

출처 및 근거

ORD 기록: ord-1e78007a2b64499bb8be2f94a3d06da2
출처 데이터셋: uspto-grants-1986_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04604464

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