참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Formic Acid | HCID 284 | — |
| 반응물 | Formamide | HCID 713 | — |
| 반응물 | Sodium Dithionite | HCID 24489 | — |
| 반응물 | 6-Amino-1,3-bis(cyclopropylmethyl)uracil | HCID 18624515 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 생성물 | 1,3-Dicyclopropylmethyl xanthine | HCID 15291303 | — |
반응 단계
1,3-Di-cyclopropylmethyl xanthine was prepared using an analogous procedure to that described in Chem. Berichte 88, 1306-1312, 1955: 20.2 g (0.0855 mol) of 1,3-dicyclopropylmethyl-6-amino-uracil was dissolved in 100 ml of formamide, then 5.9 g sodium nitrite was added and at 60° C. 13.4 ml formic acid was added slowly with stirring. After the colour had changed from yellow to violet, the mixture was heated up to 100° C. and 3.1 g of sodium dithionite (Na2S2O4) was added in small portions.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05734051 |
|---|
| 출처 데이터셋 | uspto-grants-1998_03 |
|---|
| ORD ID | ord-3f3ffc7a6ed242c8bda616b6d51cef03 |
|---|
| 출처 메모 | uspto-grants-1998_03 |
|---|
