Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 4-Fluorobenzoic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | p-Fluorotoluene | HCID 9603 | — |
| 촉매 | Cobalt(II) acetate tetrahydrate | HCID 61372 | — |
| 촉매 | Sodium Bromide | HCID 253881 | — |
| 촉매 | Sodium Acetate | HCID 517045 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Fluorobenzoic Acid | HCID 9973 | 86.6% |
반응 단계
The test described in Example 1 was repeated using 300 g of p-fluorotoluene, 660 g of acetic acid, 132 g of water, 6 g of cobalt acetate tetrahydrate, 5 g of sodium bromide and 5 g of sodium acetate. In a reaction time of 240 minutes, after conventional work-up, 330.5 g of p-fluorobenzoic acid (86.6% of the theory) was obtained, with a purity of 99.9%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04605757 |
| 출처 데이터셋 | uspto-grants-1986_08 |
| ORD ID | ord-1fce89aec2444e30b48c457d6650fca9 |
| 출처 메모 | uspto-grants-1986_08 |