Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(2-Acetylphenyl)acetamide → N-[2-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(2-Acetylphenyl)acetamide | HCID 21306 | — |
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-[2-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]acetamide | HCID 54331422 | 63.6% |
반응 단계
A suspension of 48 g of N-[2-(1-oxo-1-ethanyl)phenyl]acetamide and 38 g of N,N-dimethylformamide dimethyl acetal in 150 ml of toluene was heated at reflux for about 16 hours, then concentrated in vacuo to a solid. The solid was recrystallized from 1-chlorobutane to yield 40 g of the title compound; m.p. 90°-95° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04606755 |
| 출처 데이터셋 | uspto-grants-1986_08 |
| ORD ID | ord-93ec883c9ccb4b28914aad0f2c2c7668 |
| 출처 메모 | uspto-grants-1986_08 |