Thionyl Chloride → Benzoyl chloride, 4-(hexyloxy)-

반응식

S(Cl)([Cl:3])=O.[CH2:5]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>>[CH2:5]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([Cl:3])=[O:17])=[CH:14][CH:13]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 708344-(Hexyloxy)benzoic acid

생성물 1

HCID 170235Benzoyl chloride, 4-(hexyloxy)-수율 98%

실험 절차

Thionyl chloride (485 g of 98%, 4.00 mol) was added dropwise to 300 g (1.35 mol) of 4-hexyloxybenzoic acid. The resulting mixture was refluxed under nitrogen for 2 hours. Distillation yielded 318 g (98%) of 4-hexyloxybenzoyl chloride [boiling point 149°-153° C. (7.5 mm)].

후처리

temperatureThe resulting mixture was refluxed under nitrogen for 2 hours
distillationDistillation

출처 및 근거

ORD 기록: ord-37bb1f97559e446dbcf78a51799a51db
출처 데이터셋: uspto-grants-1986_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04606838

반응 노트

불러오는 중…