Chlorosulfonic acid → 5-tert-Butyl-2-methoxybenzene-1-sulfonyl chloride

HRID 364890노트

반응식

HRID 364890 반응식
[CH3:1][C:2]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][CH:6]=1)([CH3:4])[CH3:3].[Cl:13][S:14](O)(=[O:16])=[O:15]>C(Cl)Cl>[CH3:4][C:2]([C:5]1[CH:10]=[C:9]([S:14]([Cl:13])(=[O:16])=[O:15])[C:8]([O:11][CH3:12])=[CH:7][CH:6]=1)([CH3:1])[CH3:3]

참가 물질

4

반응물 2

HCID 24638Chlorosulfonic acidHCID 94750p-tert-Butylanisole

생성물 1

HCID 132102315-tert-Butyl-2-methoxybenzene-1-sulfonyl chloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

12.3 g (0.075 mole) of 4-(1,1-dimethylethyl)anisole, dissolved in 30 ml of methylene chloride, are added dropwise, while cooling with ice, to 16.5 ml of chlorosulfonic acid, dissolved in 20 ml of methylene chloride. The mixture is stirred for 40 minutes and is then poured into ice water. The organic phase is separated off, washed with water, dried with MgSO4 and concentrated.

후처리

  1. additionare added dropwise
  2. customThe organic phase is separated off
  3. washwashed with water
  4. dry with materialdried with MgSO4
  5. concentrationconcentrated

출처 및 근거

ORD 기록
ord-9e2e5c0e0d1446c3a6f29477aee1c55f
출처 데이터셋
uspto-grants-1986_08
특허 번호
US04607030

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