Ammonia → 5-(Tert-butyl)-2-methoxybenzenesulfonamide
반응식
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:13](Cl)(=[O:15])=[O:14])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1)([CH3:4])[CH3:3].[NH3:17]>CC(C)=O>[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:13]([NH2:17])(=[O:15])=[O:14])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1)([CH3:4])[CH3:3]참가 물질
4
실험 절차
25.3 g (0.1 mole) of 3-(1,1-dimethylethyl)-6-methoxybenzenesulfonyl chloride are dissolved in a little acetone and the solution is added dropwise slowly, at room temperature, to 100 ml of concentrated ammonia solution. The mixture is stirred for 30 minutes at room temperature and poured into ice water. After acidification with concentrated hydrochloric acid the product is filtered off with suction. It is recrystallized from isopropanol.
후처리
- filtrationAfter acidification with concentrated hydrochloric acid the product is filtered off with suction
- customIt is recrystallized from isopropanol
출처 및 근거
- ORD 기록
- ord-837fffe468e44291a343d2f26f760701
- 출처 데이터셋
- uspto-grants-1986_08
- 특허 번호
- US04607030
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