Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethylparaben → Ethyl 4-[2-Oxo-2-(phenylmethoxy)ethoxy]benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethylparaben | HCID 8434 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Benzyl bromoacetate | HCID 62576 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Ethyl 4-[2-Oxo-2-(phenylmethoxy)ethoxy]benzoate | HCID 53990693 | 99% |
반응 단계
A mixture of ethyl p-hydroxybenzoate (4.98 g), benzyl bromoacetate (4.75 ml) and K2CO3 (4.14 g) was stirred for 15 hr in 30 ml of DMF. The reaction mixture was diluted with water (200 ml) and extracted with a 1:1 ether:hexane mixture. The combined organic extracts were washed (water, brine), dried (Na2SO4), filtered, and evaporated leaving 9.3 g, (99%) of the title compound as a heavy oil; TLC, Rf =0.71, Et2O: hexane (1:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05414132 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-76c44d27eb4b427882d1bb80398ab9ef |
| 출처 메모 | uspto-grants-1995_05 |