Glutamic acid diethyl ester hydrochloride → N-(3,5-diacetamido-2,4,6-triiodobenzoyl)-L-glutamic acid diethyl ester
반응식
[C:1]([NH:4][C:5]1[C:6]([I:20])=[C:7]([C:11]([I:19])=[C:12]([NH:15][C:16](=[O:18])[CH3:17])[C:13]=1[I:14])[C:8](Cl)=[O:9])(=[O:3])[CH3:2].Cl.[CH2:22]([O:24][C:25](=[O:35])[C@H:26]([CH2:28][CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])[NH2:27])[CH3:23]>>[CH2:22]([O:24][C:25](=[O:35])[C@H:26]([CH2:28][CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])[NH:27][C:8](=[O:9])[C:7]1[C:6]([I:20])=[C:5]([NH:4][C:1](=[O:3])[CH3:2])[C:13]([I:14])=[C:12]([NH:15][C:16](=[O:18])[CH3:17])[C:11]=1[I:19])[CH3:23]참가 물질
3
실험 절차
Following the procedure of example 13, 155 g (65%) of product is synthesized from 192 g (0.3 Mol) 3,5-diacetamido-2,4,6-triiodobenzoyl chloride and 108 g (0.45 Mol) L-glutamic acid diethyl ester hydrochloride.
출처 및 근거
- ORD 기록
- ord-7c8bb76113ea404e83e7b0b31b694fc0
- 출처 데이터셋
- uspto-grants-1986_08