Diethyl Ether → 2-[4-(Dimethylamino)styryl]-1-dodecylpyridinium bromide

HRID 365123노트

반응식

HRID 365123 반응식
[Br-:1].[CH2:2]([N+:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:20])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[CH3:21][N:22]([CH3:31])[C:23]1[CH:30]=[CH:29][C:26]([CH:27]=O)=[CH:25][CH:24]=1.N1CCCCC1.CCOCC>C(O)C>[Br-:1].[CH3:21][N:22]([CH3:31])[C:23]1[CH:30]=[CH:29][C:26]([CH:27]=[CH:20][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][N+:14]=2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])=[CH:25][CH:24]=1

참가 물질

6

반응물 4

HCID 3283Diethyl EtherHCID 74794-(Dimethylamino)BenzaldehydeHCID 8082PiperidineHCID 219878411-Dodecyl-2-methylpyridinium bromide

생성물 1

HCID 704553152-[4-(Dimethylamino)styryl]-1-dodecylpyridinium bromide수율 50.7%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

1-Dodecyl-2-methylpyridinium bromide (3.42 g, 0.01 mole) and 4-dimethylaminobenzaldehyde (1.6 g, 0.011 mole) were refluxed in ethanol (15 ml) in the presence of piperidine (0.2 ml) under nitrogen for two hours. The solution was cooled and ether was added when an orange solid crystallised which was collected giving 2-[4-(dimethylamino)styryl]-1-dodecylpyridinium bromide quarter hydrate (2.4 g), melting point 197°-198° C.

후처리

  1. temperatureThe solution was cooled
  2. customcrystallised which
  3. customwas collected

출처 및 근거

ORD 기록
ord-e93c4077a2d647a38d8aceb4ff11183f
출처 데이터셋
uspto-grants-1986_08
특허 번호
US04608379

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