Diethyl Ether → 2-[4-(Diethylamino)styryl]-1-dodecylpyridinium bromide hemihydrate

HRID 365124노트

반응식

HRID 365124 반응식
[Br-:1].[CH2:2]([N+:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:20])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[CH2:21]([N:23]([CH2:32][CH3:33])[C:24]1[CH:31]=[CH:30][C:27]([CH:28]=[O:29])=[CH:26][CH:25]=1)[CH3:22].N1CCCCC1.CCOCC>C(O)C>[OH2:29].[Br-:1].[CH2:32]([N:23]([CH2:21][CH3:22])[C:24]1[CH:31]=[CH:30][C:27]([CH:28]=[CH:20][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][N+:14]=2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])=[CH:26][CH:25]=1)[CH3:33].[CH2:21]([N:23]([C:24]1[CH:25]=[CH:26][C:27]([CH:28]=[CH:20][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][N+:14]=2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])=[CH:30][CH:31]=1)[CH2:32][CH3:33])[CH3:22].[Br-:1]

참가 물질

6

반응물 4

HCID 3283Diethyl EtherHCID 8082PiperidineHCID 671144-(Diethylamino)benzaldehydeHCID 219878411-Dodecyl-2-methylpyridinium bromide

생성물 1

HCID 1317148382-[4-(Diethylamino)styryl]-1-dodecylpyridinium bromide hemihydrate수율 41.2%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

1-Dodecyl-2-methylpyridinium bromide (3.42 g), 0.01 mole) and 4-diethylaminobenzaldehyde (1.9 g), 0.011 mole) were refluxed in ethanol (15 ml) in the presence of piperidine (0.2 ml) under nitrogen for two hours. The solution was cooled and ether was added when an orange solid crystallised which was collected giving 2-[4-(diethylamino)styryl]-1-dodecylpyridinium bromide hemihydrate, (2.1 g), melting point 199°-200° C.

후처리

  1. temperatureThe solution was cooled
  2. customcrystallised which
  3. customwas collected

출처 및 근거

ORD 기록
ord-940de61dbdf347a2848357fa33583c82
출처 데이터셋
uspto-grants-1986_08
특허 번호
US04608379

반응 노트

불러오는 중…