참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | 2-Methylpyridine | HCID 7975 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 4-(Diethylamino)benzaldehyde | HCID 67114 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 1-Benzyl-2-[4-(diethylamino)styryl]pyridinium bromide | HCID 70455530 | 44.4% |
반응 단계
2-Picoline (9.3 g, 0.1 mole) and benzyl bromide (17.1 g, 0.1 mole) were refluxed in isopropanol (50 ml) overnight. The solvent was evaporated giving an oil which was heated at 100° C. for six hours. The resulting crude oil (8.5 g, 0.032 mole) and 4-diethylaminobenzaldehyde (6.0 g, 0.033 mole) were refluxed in methanol (40 ml) in the presence of piperidine (0.2 ml) under nitrogen for three hours. On cooling dark-coloured crystals were obtained which were collected to give 1-benzyl-2-[4-(diethylamino)styryl]pyridinium bromide (6.2 g), melting point 231°-233° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04608379 |
|---|
| 출처 데이터셋 | uspto-grants-1986_08 |
|---|
| ORD ID | ord-d040665acb754439b3780d1ccacf8331 |
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| 출처 메모 | uspto-grants-1986_08 |
|---|
