Diethyl Ether → 1-Dodecyl-2-[(4-piperidino)styryl]pyridinium bromide

HRID 365127노트

반응식

HRID 365127 반응식
[Br-:1].[CH2:2]([N+:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:20])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[N:21]1([C:27]2[CH:34]=[CH:33][C:30]([CH:31]=O)=[CH:29][CH:28]=2)[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1.N1CCCCC1.CCOCC>CO>[Br-:1].[CH2:2]([N+:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH:20]=[CH:31][C:30]1[CH:29]=[CH:28][C:27]([N:21]2[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]2)=[CH:34][CH:33]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

참가 물질

6

반응물 4

HCID 3283Diethyl EtherHCID 8082PiperidineHCID 2913544-(Piperidin-1-yl)benzaldehydeHCID 219878411-Dodecyl-2-methylpyridinium bromide

생성물 1

HCID 704551531-Dodecyl-2-[(4-piperidino)styryl]pyridinium bromide수율 24.7%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

1-Dodecyl-2-methylpyridinium bromide (2.3 g, 0.0067 mole) and 4-piperidinobenzaldehyde (1.27 g, 0.0067 mole) were refluxed in methanol (20 ml) in the presence of piperdine (0.1 ml) under nitrogen for three hours. The solution was cooled and addition of ether gave a crystalline solid which was collected giving 1-dodecyl-2-[(4-piperidino)styryl]pyridinium bromide (0.85 g), melting point 203°-205° C.

후처리

  1. temperatureThe solution was cooled
  2. customgave a crystalline solid which
  3. customwas collected

출처 및 근거

ORD 기록
ord-8c2c0cba5a8949d388c880a375e24e4b
출처 데이터셋
uspto-grants-1986_08
특허 번호
US04608379

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