Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Naphthalenecarboxaldehyde → HCID 13105363, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Naphthalenecarboxaldehyde | HCID 6201 | — |
| 반응물 | (5-Carboxypentyl)triphenylphosphanium bromide | HCID 2779280 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | HCID 13105363 | HCID 13105363 | — |
반응 단계
Triphenyl (5-carboxypentyl)phosphonium bromide (937 mg, 2.1 mmole) and 2-napthaldehyde (300 mg, 1.92 mmole) were dissolved in DMSO (50 mL, freshly distilled from CaH2) and potassium t-butoxide (540 mg, 4.8 mmole) was added. After stirring for 30 minutes the reaction was quenched with saturated NH4Cl solution (25 mL) and poured into ether. The ether layer was dried with saturated NaCl and MgSO4 and the solvent was evaporated. The resulting 1:1 mixture E/Z isomers were separated with flash chromatography eluting with ether/hexane/formic acid (10:89:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04608390 |
| 출처 데이터셋 | uspto-grants-1986_08 |
| ORD ID | ord-3ad2552c093947eba337459f5871f91e |
| 출처 메모 | uspto-grants-1986_08 |