Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 365152생성일: 2026년 10월 25일
Potassium Carbonate → 11-{1-[2-(3,4,5-Trimethoxyphenyl)ethyl]piperidin-4-yl}-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine
https://huagongshe.com/reaction/365152
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-(3,4,5-Trimethoxyphenyl)ethyl methanesulfonate | HCID 11616258 | — |
| 반응물 | 11-(piperdin-4-yl)-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine | HCID 13689358 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 11-{1-[2-(3,4,5-Trimethoxyphenyl)ethyl]piperidin-4-yl}-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine | HCID 13689405 | — |
반응 단계
A mixture of 11-(piperidin-4-yl)-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine (5.8 g, 0.022 mole), K2CO3 (11.0 g) and 2-(3,4,5-trimethoxyphenyl)ethyl methanesulfonate (7.53 g, 0.026 mole) in 120 ml dimethylformamide was heated at 70° C. for 4.5 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04608374 |
|---|
| 출처 데이터셋 | uspto-grants-1986_08 |
|---|
| ORD ID | ord-32ab08def0fc4a98914fcd008c84b192 |
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| 출처 메모 | uspto-grants-1986_08 |
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