Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Dimethylhydrazine → 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Dimethylhydrazine | HCID 1322 | — |
| 반응물 | Diethyl methylmalonate | HCID 11857 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone | HCID 12818853 | — |
반응 단계
Diethyl methylmalonate and N,N'-dimethylhydrazine are heated under reflux for 170 hours in methanol in the presence of sodium methylate under an atmosphere of nitrogen. 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone is obtained in the form of colorless crystals which, after recrystallization from ethyl acetate, melt at 87°-89° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04608383 |
| 출처 데이터셋 | uspto-grants-1986_08 |
| ORD ID | ord-da58efdd8cfd44639ad1ce4e0173a134 |
| 출처 메모 | uspto-grants-1986_08 |