Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Pyridine-3,5-dicarboxylic acid methyl ester hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 3,5-Pyridinedicarboxylic acid | HCID 10366 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | Pyridine-3,5-dicarboxylic acid methyl ester hydrochloride | HCID 70274642 | — |
반응 단계
Pyridine-3,5-dicarboxylic acid (5.00 g, 29.9 mmol) was stirred in CH3OH (100 mL), cooled in an ice bath, and treated dropwise with thionyl chloride (17.45 mL, 239.2 mmol). After 0.5 hr, the reaction mixture was refluxed for 48 hrs. Concentration to dryness gave the title compound as an off-white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06127366 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-1b62a4aa5e3545ef8cc070eb914f7418 |
| 출처 메모 | uspto-grants-2000_10 |