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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 36554생성일: 2026년 10월 23일

Citric Acid → DL-Malate

https://huagongshe.com/ko/reaction/36554

반응식

참여 물질

역할이름HCID투입량
반응물Citric AcidHCID 311—
반응물Malic AcidHCID 525—
반응물delta-GluconolactoneHCID 7027—
반응물Sodium BicarbonateHCID 516892—
생성물DL-MalateHCID 160434—
생성물Monosodium CitrateHCID 23666341—

반응 단계

Process: Apply crystallized citric acid, then heat to 60° C. and wet with 36 ml of gluconic acid delta-lactone solution (10 parts of gluconic acid delta-lactone to 5 parts of water); apply malic acid, then allow sodium bicarbonate I to react to give monosodium citrate and malate and then allow sodium bicarbonate II, calcium carbonate and potassium bicarbonate to undergo partial reaction (partial conversion to the citrate). Then cover the surface with citric acid powder. Finally allow sodium carbonate to undergo partial reaction, and dry in vacuo. This effervescent base is mixed with 500 parts of aspirin and with corresponding additives.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05415870
출처 데이터셋uspto-grants-1995_05
ORD IDord-b21f295b723640c999e6fa015768ecb3
출처 메모uspto-grants-1995_05