Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3,5-Trichlorobenzene → Ammonia
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3,5-Trichlorobenzene | HCID 7950 | — |
| 반응물 | 1,3,5-Trifluorobenzene | HCID 9745 | — |
| 반응물 | 3,5-Difluoroaniline | HCID 96595 | — |
| 생성물 | Ammonia | HCID 222 | — |
| 생성물 | 1,3,5-Trifluorobenzene | HCID 9745 | — |
| 생성물 | 3,5-Difluoroaniline | HCID 96595 | — |
반응 단계
One embodiment of the present invention relates to the discovery that 3,5-difluoroaniline can be synthesized at high yields and high purity by fluorinating 1,3,5-trichlorobenzene in the presence of a polar solvent to make an intermediate 1,3,5-trifluorobenzene, and then aminating the 1,3,5-trifluorobenzene in the presence of aqueous or anhydrous ammonia to obtain the desired 3,5-difluoroaniline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06127577 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-4b08970ec16c4bdc8e67712613b25e80 |
| 출처 메모 | uspto-grants-2000_10 |