2-Bromobenzyl bromide → 1-Bromo-2-(methoxymethyl)benzene
반응식
[Br:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4]Br.[CH3:10][O-:11].[Na+]>CO>[Br:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][O:11][CH3:10]참가 물질
4
실험 절차
685 g (2.74 mol) of o-bromobenzyl bromide was refluxed with 2.74 mol of a 30% strength sodium methylate solution in methanol for 15 hours. After the mixture had cooled to room temperature it was evaporated down, taken up in ethyl acetate, and washed with water. After the organic phase had been dried over sodium sulfate, it was again evaporated down. There was obtained 478.2 g (87%) of the title substance as a colorless liquid.
후처리
- customwas evaporated down
- washwashed with water
- dry with materialAfter the organic phase had been dried over sodium sulfate, it
- customwas again evaporated down
- customThere was obtained 478.2 g (87%) of the title substance as a colorless liquid
출처 및 근거
- ORD 기록
- ord-38dfa61d18674d36a2a17eda1d4b5eb3
- 출처 데이터셋
- uspto-grants-1995_05
- 특허 번호
- US05416068
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