Hydromorphone Hydrochloride → Hydromorphone

HRID 366283

반응식

HRID 366283 반응식
[CH3:1][N:2]1[C@@H:19]2[CH2:20][C:7]3=[CH:8][CH:9]=[C:10]([OH:21])[C:11]4[O:12][C@H:13]5[C:14]([CH2:16][CH2:17][C@@H:18]2[C@:5]5([C:6]=43)[CH2:4][CH2:3]1)=[O:15].Cl>O>[CH3:1][N:2]1[C@@H:19]2[CH2:20][C:7]3=[CH:8][CH:9]=[C:10]([OH:21])[C:11]4[O:12][C@H:13]5[C:14]([CH2:16][CH2:17][C@@H:18]2[C@:5]5([C:6]=43)[CH2:4][CH2:3]1)=[O:15]

참가 물질

3

반응물 1

HCID 5462347Hydromorphone Hydrochloride

생성물 1

HCID 5284570Hydromorphone

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Hydromorphone beads were prepared by dissolving hydromorphone HCl in water, adding Opadry®, and mixing for about 1 hour, and then spraying onto nu pariel 18/20 beads using a Wurster insert. The resultant coated beads were then overcoated with Opadry® Y-5-1442 light pink (15% w/w). The beads were then overcoated with a aqueous dispersion of Aquacoat® to a 15% weight gain according to Table 15 below:

후처리

  1. additionadding Opadry®
  2. additionmixing for about 1 hour

출처 및 근거

ORD 기록
ord-d2a3b43270744e1aac32e5ba82e46434
출처 데이터셋
uspto-grants-2000_10
특허 번호
US06129933

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